The HopF family of Pseudomonas syringae type III secreted effectors Timothy Lo, Noushin Koulena, Derek Seto, David S. Guttman, and Darrell Desveaux Abstract Pseudomonas syringae is a bacterial phytopathogen that utilizes the type III secretion system to inject effector proteins into plant host cells. Pseudomonas syringae can infect a wide range of plant hosts, including […]
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Expanded type III effector recognition by the ZAR1 NLR protein using ZED1-related kinases
Expanded type III effector recognition by the ZAR1 NLR protein using ZED1-related kinases Derek Seto, Noushin Koulena, Timothy Lo, Alexandra Menna, David S. Guttman and Darrell Desveaux Abstract Nucleotide-binding domain and leucine-rich repeat domain containing (NLR) proteins are sentinels of plant immunity that monitor host proteins for perturbations induced by pathogenic effector proteins. Here we show […]
Read MoreImage-Based Quantification of Plant Immunity and Disease
Image-Based Quantification of Plant Immunity and Disease Bradley Laflamme, Maggie Middleton, Timothy Lo, Darrell Desveaux, and David S. Guttman Abstract Measuring the extent and severity of disease is a critical component of plant pathology research and crop breeding. Unfortunately, existing visual scoring systems are qualitative, subjective, and the results are difficult to transfer between research […]
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A Mesoscale Abscisic Acid Hormone Interactome Reveals a Dynamic Signaling Landscape in Arabidopsis
We have defined a focused ABA signaling network of over 500 interactions among 138 proteins. The network can be queried functionally to define genes involved in ABA signaling. When merged with global expression patterns centered on abiotic stresses, the ABA network reveals specific modules related to each stress condition.
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The type III effector HopF2Pto targets Arabidopsis RIN4 protein to promote Pseudomonas syringae virulence
The type III effector HopF2Pto targets Arabidopsis RIN4 protein to promote Pseudomonas syringae virulence Wilton M, Subramaniam R, Elmore J, Felsensteiner C, Coaker G, Desveaux D Proc. Natl. Acad. Sci. U.S.A. 2010 Feb;107(5):2349-54 PubMed PMID: 20133879 Abstract Plant immunity can be induced by two major classes of pathogen-associated molecules. Pathogen- or microbe-associated molecular patterns (PAMPs […]
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Found in translation: high-throughput chemical screening in Arabidopsis thaliana identifies small molecules that reduce Fusarium head blight disease in wheat
Found in translation: high-throughput chemical screening in Arabidopsis thaliana identifies small molecules that reduce Fusarium head blight disease in wheat Schreiber KJ, Nasmith CG, Allard G, Singh J, Subramaniam R, Desveaux D Mol. Plant Microbe Interact. 2011 Jun;24(6):640-8 PubMed PMID: 21303209 Abstract Despite the tremendous economic impact of cereal crop pathogens such as the fungus […]
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The Arabidopsis ZED1 pseudokinase is required for ZAR1-mediated immunity induced by the Pseudomonas syringae type III effector HopZ1a
The Arabidopsis ZED1 pseudokinase is required for ZAR1-mediated immunity induced by the Pseudomonas syringae type III effector HopZ1a Lewis JD, Lee AH, Hassan JA, Wan J, Hurley B, Jhingree JR, Wang PW, Lo T, Youn JY, Guttman DS, Desveaux D Proc. Natl. Acad. Sci. U.S.A. 2013 Oct;: PubMed PMID: 24170858 Abstract Plant and animal pathogenic […]
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