Expanded type III effector recognition by the ZAR1 NLR protein using ZED1-related kinases
Derek Seto, Noushin Koulena, Timothy Lo, Alexandra Menna, David S. Guttman and Darrell Desveaux
Nucleotide-binding domain and leucine-rich repeat domain containing (NLR) proteins are sentinels of plant immunity that monitor host proteins for perturbations induced by pathogenic effector proteins. Here we show that the Arabidopsis ZAR1 NLR protein requires the ZRK3 kinase to recognize the Pseudomonas syringae type III effector (T3E) HopF2a. These results support the hypothesis that ZAR1 associates with an expanded ZRK protein family to broaden its effector recognition spectrum.